Asian Cohort for Alzheimer’s Disease (ACAD)

What is the study about?

This study aims to compile a robust sample of Asian American and Canadian subjects for Alzheimer’s disease (AD) research. Asians are the fastest-growing population in both countries, yet they are underrepresented in AD research. ACAD aims to address this gap by starting with a cohort of individuals of Chinese ancestry in Toronto and extending to other major Asian populations in both countries. We also study how genetics and other non-genetic factors of Asian people, may be associated with risks for developing dementia (severe memory problems) in their old age.

Eligibility – Who can participate?

Older adults with either:

• Alzheimer’s Disease
• Cognitively healthy people

All participants must:

• be age 60 or above
• Identify as Chinese or Chinese Canadian and lives in Canada
• Ability to communicate in English, Mandarin, or Cantonese 

Time requirement

The study lasts for a maximum of 5 years, including initial participation and follow-up every two years. Each participation of the study will take 3-4 hours and can be completed in 1-2 visits. For participants with Alzheimer’s Disease, we require a study partner.

The participant will go through in-person and/or virtual interviews and assessments with the study team members and a physician, and will also provide blood (preferrable) or saliva samples. Compensation is provided for your and study partner’s time and effort.

The initial participation and follow-ups involves:

• Questionnaires (Demographics, early life experience and physical activities, health and family history, research participation experience)
• Functional assessment and several cognitive tests
• A brief neurological examination perform by a physician
• Provide blood(preferrable) or saliva samples