Interventional Study

Enhancing Frontal Lobes Plasticity and Function in Patients with Mild Cognitive Impairment (PAS-MCI)

Study Investigator:Dr. Tarek Rajji
Site: Centre for Addiction and Mental Health  | Address: 1001 Queen St W, Toronto, ON M6J 1H4 Opens in new tab
Area of Focus: Healthy volunteer | Mild cognitive impairment
Minimum Participant Age: 60+ | 65+

 

What is the study about?

This study is assessing the use of a novel brain stimulation technique called Transcranial Magnetic Stimulation to determine if it can improve memory and thinking processes in people diagnosed with Mild Cognitive Impairment. We are conducting this experiment to assess whether TMS can strengthen the connection between different cells in the frontal area of the brain that is especially relevant to attention and memory in Mild Cognitive Impairment, a condition that often precedes dementia.

 

Eligibility–Who can participate?

Participants must:

  • Be 60 years of age or older
  • Have a diagnosis of mild cognitive impairment or be a healthy volunteer

 

Time requirement:

Participants will undergo treatment sessions that range from 1.5 to 3 hours at CAMH, 5 days a week, over a total of 2 weeks. In addition, participants will complete clinical and cognitive assessments at baseline, after treatment, and again 3 weeks later.

 

Study Video

Advances in Dementia Research Webinar- Listen to Dr. Tarek Rajji (Principal Investigator) discuss the PAS-MCI study in further detail: 

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Disclaimer

The listing of a study on the TDRA’s Research Studies Portal is for informational purposes only. The safety, efficacy or scientific validity of the studies listed here have not been evaluated by The Alzheimer Society of Toronto (AST) or the Toronto Dementia Research Alliance (TDRA). The TDRA is an academic coalition among the University of Toronto and Baycrest, the Centre for Addiction and Mental Health, Ontario Shores Centre for Mental Health Sciences, Sunnybrook Health Sciences Centre, and the University Health Network. The information collected will be kept and guarded by TDRA. Choosing to participate in a study is an important personal decision. Before you participate in a study, you should make sure you understand the risks and potential benefits and discuss all options with your health care provider(s).